355 E 116th St is located in East Harlem, also known as Spanish Harlem or El Barrio, in Manhattan, New York City. This vibrant neighborhood has a rich cultural history and is known for its diverse community. The area's population is predominantly Hispanic, with a mix of other ethnicities contributing to the cultural tapestry.

East Harlem has experienced fluctuations in crime rates, but efforts have been made to improve safety over the years. It's advisable to check the latest statistics from local sources or NYPD reports for the most accurate information. The neighborhood is served by Community School District 4, which includes a mix of public, charter, and private schools. School ratings can vary, so researching individual schools would be beneficial.

East Harlem offers a variety of amenities, including grocery stores, local eateries, community parks like Thomas Jefferson Park, and cultural institutions such as the Museum of the City of New York. The neighborhood is well-connected by public transportation, making it convenient to access other parts of Manhattan. The area has been undergoing gentrification, with new businesses and housing developments springing up. The average household income in East Harlem may be lower compared to other Manhattan neighborhoods, but nearby districts like the Upper East Side have significantly higher average incomes. While detailed job growth statistics are not immediately available, the area's proximity to Manhattan's business hubs generally offers diverse employment opportunities within commuting distance.